Dear ABRF,
Do you know how the pI of a protein would change if arginine becomes
dimethylated (pKa value of dimethylarginine?)?
Does anybody know what the most sensitive way of detecting this
modification in a purified protein would be and how much material would be
needed?
Thank you for your time and help!
Juri Rappsilber
Protein Interaction Laboratory
University of Southern Denmark
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