Has anyone run intact protein with molecular weight larger than 40 k on
LCQ-Deca? We just had our LCQ-deca installed and we have some s/n problem
especially when we are working with intact proteins. The TIC value is much
higher from Deca than from LCQ- classic but the s/n ratio is much poorer. The
averaged spectra is so poor that we can not do any deconvolution for protein
larger than 40 k. I am wondering if this is just our LCQ-deca problem or if it
is a problem with all LCQ-deca.
Rong-Rong Zhu
BASF Bioresearch Corp.
508-849-2770
zhur@basf.com
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