Re: aminoacids on trityl resin

From: NobleRN@pebio.com
Date: Wed May 17 2000 - 14:19:08 EDT


Daniela,

>From the 1999 Novabiochem Catalog & Peptide Synthesis Handbook, p. 172, there
are three other references you might check:

1.) K. Barlos, et.al., (1988) Liebigs Ann. Chem. 1079.
2.) K. Barlos, et.al. in "Peptides 1992, Proc. 22nd European Peptide
Symposium", C.H. Sneider & A.N. Eberle (Eds.), ESCOM, Leiden, 1993, pp. 281.
3.) M. Schuster, et.al. (1996) Angew. Chem. Int. Engl. Ed., 35, 1979.

Hope this helps.

Best regards, Dick

Richard, Noble, Ph.D.
PE Biosystems
850 Foster City Blvd.
Foster City, CA 94404

email: noblern@pebio.com
fax: 650-638-6311

Fattori Daniela <FattoriD@irbm.it> on 05/17/2000 09:39:05 AM

To: Recipients of ABRF List <abrf@aecom.yu.edu>
cc: (bcc: Richard Noble/FOS/PEC)

Subject: aminoacids on trityl resin

Dear all,
I'm in the need to load an aminoacid on trityl resin through the amino
group, but the only reference I could find has been:

P. Athanassopoulos et al., Poster 316 presented at the 24th European Peptide
Symposium, Edimburgh, (1996) (not published in symposium proceedings).

Is there someone who can tell me a little bit more ? In particular, how to
avoid the competing loading of the carboxy-terminus ?
Thanks.
     Daniela

**********************
Daniela Fattori Ph.D
Sen. Research Chemist
IRBM
Biotechnology Dep.
Via Pontina km.30. 600
00040 Pomezia (Roma)
**********************





This archive was generated by hypermail 2b29 : Thu May 18 2000 - 09:47:35 EDT