Removing TFA from peptide -Reply

From: Tom Haas, Ph.D. (haast@ccf.org)
Date: Fri Jul 28 2000 - 13:26:52 EDT


Bob, here is an easy method that I use.
Dissolve the peptide in 100 mM HCl. Wait ~1 minute. Freeze in liquid N2. Vacuum Dry. >95% TFA is removed.

Tom Haas
Molecular Cardiology
Cleveland Clinic Foundation

>>> Bob Lee <boblee@uic.edu> 07/27/00 11:10am >>>
Hi,

I know that removing TFA from peptide has been discussed before but I
cannot find my file. I need a good and convenient method for removing TFAfrom peptide after c-18 column. Thanks.

Bob



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