The paper you want is Johnson, R. S. and Walsh, K. A., Sequence analysis of
peptide mixtures by automated integration of Edman and mass spectrometric data,
Protein Science, 1992, 1(9), 1083-1091. The program was called MADMAE.
-- John Cottrell Matrix Science Ltd. 30 Harcourt Street London W1H 1DT, UK Tel: +44 20 7723 2142 Fax: +44 20 7725 9360 jcottrell@dial.pipex.com http://www.matrixscience.comUlf Hellman wrote:
> Dear ABRF'ers, > We sometimes face the problem of reading an Edman result with more > than one (equal signals) residue per cycle. Given the masses (as obtained > by MALDI) of the peptides in the sample, one feels it would be easy to > deconvolute the correct sequences, but it takes a while to do manually, and > it is not easy. Has anyone seen a program that could help? > Another semirelated question: Does anyone know of a program like BLAST, > that allows input of several peptide sequences. That will be useful if > you've obtained a few sequences and want to look for a matching protein > that includes all peptides. > Regards /Ulf > > Ulf Hellman > Prof., Ph. D. > Ludwig Institute for Cancer Research > Box 595 > SE-751 24 Uppsala > Sweden > > Phone +46 18 160423 > Fax +46 18 160420 > e-mail <ulf.hellman@licr.uu.se> > alt. <cykeldoktorn@hotmail.com>
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