Re: autosamplers for LC/MS

From: D Carl (carl287@yahoo.com)
Date: Fri Nov 24 2000 - 10:04:37 EST


Hi Larry,

I have evaluated different types of autosamplers. I
purchased HP 1100s. This was partly because of the
data capture and evaluation software that was included
(as a stand alone). The pump flow was always
consistant as well. A draw back was the lack of 96
well plate autosampler.

Good luck,

Carl Dourambeis
President
Custom Organic Molecular Synthesis (COMSPHARMA) Inc.
287 Maclean Avenue
Pointe Claire, Quebec
H9R 5Y1
Tel: (514) 695-0028
Fax: (514) 695-0147

--- Larry David <davidl@ohsu.edu> wrote:
> Dear ABRF members,
>
> I'm currently evaluating autosamplers to replace my
> old Waters WISP. I would like an autosampler with
> refrigeration and a very low solvent path volume.
> It will be used to inject peptide digests from 2D
> gels via a Michrom trap onto a 100 um capillary
> column and LCQ. Two autosamplers that come to mind
> are the Agilent 1100 series well plate autosampler
> and the LC Packings FAMOS. Does anyone have any
> experience with these autosamplers they would like
> to share, or any suggestions for other autosamplers?
>
>
> The advantages of the Agilent autosampler are the
> price and that I already have a hand held controller
> to operate it. The disadvantage is that there is no
> software that would allow Xcalibur to control it.
> The advantage of the FAMOS is that it has been
> around longer, it can be controlled by Xcalibur, and
> it may be better suited for injections from very
> small volumes. However, are small volume injections
> really necessary if a trap is used to concentrate
> samples?
>
> Thank you in advance for your input.
>
> Sincerely,
>
> Larry David
> Associate Professor
> Oregon Health Sciences University
> davidl@ohsu.edu
>

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