Dear ABRF,
>Thank a lot for your information about solution synthesis. I have =
>another problem.
>We have some trouble while employing one product used in spps, more =
>exactly the
>(Boc-Cys-OH)2 (cystine).
>In fact employing it in a standard Fmoc synthesis we find out a broken
>peptide, with the sulfidrilic group as broken bond: the monomer appear =
>to
>be reduced by some of the reagent or monomer of the standard Fmoc =
>protocol(piperidine?).
>We use TFA 95%, TIS 2,5%, H2O 2,5% as cleavage mixture.
>Is there any possibility that this product could be broken by some other
>reagent?
>We would like to have your opinion in this matter, with some reference
>about it,if it is possible.
>Best REGARDS
>E. Millo
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