Re: DNA sequencer

From: Jeremy Medalle (medallj@mail.rockefeller.edu)
Date: Thu Feb 15 2001 - 13:19:23 EST


Hi,

If you are not a high throughput DNA sequencing facility, capillary
technology is not ideal. ...go with slab technology. (I.e. Basestation)
Materials for slab runs can be kept indefinitely.

Issues with 3700:

**1. Polymer life time: 5 days: $365.00

If you use half the bottle(abut 6 runs) and have one or two runs within the
time period. You have wasted the polymer by not having enough runs.

Operating use of polymer: bubble remove, installing new polymer, restarting
3700 machine.

2. Clean-ups: Edge BioSystems:96 Well Spin Column(50/pk): $2544.90
      (50.90/plate)

In incomplete 96 tray, you can not save the column not is use.

3. Reaction/Elution Trays: 3.50 per plate

You need twice amount of trays. One for the thermocycler and other for
cleanup.

These are the major waste for us. Last year we did 1-2 megabase per week.

-- 
Jeremy Medalle
Lab Coordinator
The Rockefeller University
1240 York Ave
Box 105
NY, NY 10021

http://www.protein13-pc.rockefeller.edu



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