FMOC removal?

From: Stephanie Michaud (Michaud@adherex.com)
Date: Fri Apr 06 2001 - 15:24:56 EDT

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Dear All,

I would like to react FMOC-Cys-NH2 via the sulfhydryl group with an
N-bromoacetylated peptide to form a thioether. Will using TRIS as base (in
DMF) cause significant removal of the FMOC group? Thanking you in advance.

Stephanie

Stephanie Michaud, Ph. D.
Project Leader
Adherex Technologies Inc.
ph 613.738.8000 ext227
fx 613.738.9060
email michaud@adherex.com

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