Cy Dyes and MALDI

From: Frank Bruce (bfrank@valigen.net)
Date: Tue Apr 17 2001 - 09:28:36 EDT


I would be interested in knowing the effect of Cy dyes on MALDI of
oligonucleotides as well.

Thanks in advance!

Bruce.

Bruce Frank, Ph.D.
Director, Chemistry
ValiGen
300 Pheasant Run
Newtown, PA 18940
Phone: 215-504-4444 x214
Fax: 215-504-4545
email: bfrank@valigen.net

-----Original Message-----
From: Greg Grant [mailto:ggrant@pcg.wustl.edu]
Sent: Monday, April 16, 2001 1:10 PM
To: Recipients of ABRF List
Subject:

Dear Colleagues,

        Can anyone provide any information on the Cy 3 and Cy 5 dyes being
marketed by Amersham as to their properties and compatability with mass
spec analysis. Like, how do they interact with proteins? How sensitive are
they? Do they need to be removed prior to analysis? and anything else.

Thanks,

Gregory A. Grant
ggrant@pcg.wustl.edu
314-362-3367
FAX 314-362-4698



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