Re: PepSyn: Rink amide AM resin

From: Roger Murphy (Roger.Murphy@ludwig.edu.au)
Date: Wed May 16 2001 - 23:27:27 EDT

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<font size=3>Hi Gary,<br>
The Nle is so you can do amino acid analysis on the resin bound peptide
and determine the substitution level you've reached, i.e. how many
handles you've actually activated.<br>
Cheers,<br>
Roger<br>
<br>
At 18:32 16/05/01 -0600, Gary Van Domselaar wrote:<br>
<blockquote type=cite cite>Hey folks,<br>
<br>
I was reading in the novabiochem catalog about the Rink amide AM
resin.<br>
It states that there is a nle 'reference' amino acid situated between
the<br>
Rink amide linker and the aminomethyl polystyrene resin.&nbsp; I was
wondering,<br>
what exactly is this reference for?<br>
<br>
Thanks in advance,<br>
<br>
g.<br>
--&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
--<br>
&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
Gary Van Domselaar<br>
Ph.D.
Candidate,&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
Associate Director,<br>
Faculty of
Pharmacy,&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
Bioinformatics.org: The Open Lab<br>
University of
Alberta&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
gary@bioinformatics.org<br>
gary@penguin.pharmacy.ualberta.ca&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<a href="http://bioinformatics.org/gary" eudora="autourl">http://bioinformatics.org/gary><br>
--&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
--</font></blockquote><br>
<br>
<div>------------------------------------------------------------</div>
<div>Roger Murphy, Ph.D.</div>
<div>Biological Production Facility</div>
<div>Ludwig Institute for Cancer Research</div>
<div>Austin &amp; Repatriation Medical Centre</div>
<div>Studley Road,</div>
<div>Heidelberg,&nbsp; Vic. 3084</div>
<div>Australia.</div>
<br>
<div>Tel&nbsp; 61-3-94965463</div>
<div>Fax&nbsp; 61-3-94965436</div>
Email Roger.Murphy@Ludwig.edu.au
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