C-terminal blocking of proteins

Williams, Ken (WilliamsKR@MASPO1.MAS.YALE.EDU)
Wed, 15 Jan 1997 12:51:00 -0500 (est)

Date: Wed, 15 Jan 1997 12:51:00 -0500 (est)
From: "Williams, Ken" <WilliamsKR@MASPO1.MAS.YALE.EDU>
Subject: C-terminal blocking of proteins
To: Recipients of ABRF List <abrf@aecom.yu.edu>

One of the potential advantages of automated C-terminal sequencing is
that it would get by the problem of blocked N-terminals in proteins from
higher eukaryotes. However, this brings up the question of the extent of
C-terminal blocking in higher eukaryotes (and other organisms). Does anyone
have any data/know of any references that relate to occurrence of C-terminal
blocking?

Thanks very much,
Ken Williams