C-terminal sequencing by MALDI

falick@cgl.ucsf.edu
Mon, 20 Jan 1997 20:09:22 -0800 (PST)

From: falick@cgl.ucsf.edu
Date: Mon, 20 Jan 1997 20:09:22 -0800 (PST)
Message-Id: <199701210409.UAA17138@socrates.ucsf.EDU>
Subject: C-terminal sequencing by MALDI
To: Recipients of ABRF List <abrf@aecom.yu.edu>

Lisa Bibbs forwarded a question about C-terminal sequencing using
carboxypeptidase and MALDI. I suggest looking at D. Patterson, et al.,
Anal. Chem. 67, 3971-3978 (1995). I've seen a few new tricks since
then, but there is a list of peptides that were tried and how far
they got.

Disclaimer: All of the authors of the referenced paper work for
PerSeptive Biosystems, as do I.

Arnie Falick
PerSeptive Biosystems
falick@cgl.ucsf.edu