From: Jim Sparrow <jsparrow@athero.med.bcm.tmc.edu>
Subject: RE: Peptide synthesis
Date: Wed, 22 Jan 97 10:11:00 C
To: Recipients of ABRF List <abrf@aecom.yu.edu>
Try contacting John McMurray at jsmcmur@utmdacc.uth.tmc.edu. or an another
alternative is to use SPAR50 polyamide from Advanced ChemTech which can be
used to synthesize your peptide on, deprotected and injected after crushing
the beads to produce antibodies, see Kennedy, R.C., Dreesman, G.R., Chanh,
T.C., Boswell, R.N., Allan, J.S., Lee T-H., Essex, M., Sparrow, J.T., Ho,
D.D., and Kanda, P. Use of a Resin-Bound Synthetic Peptide for Identifying
a Neutralizing Antigenic Determinant Associated with the Human
Immunodeficiency Virus (HIV) Envelope. J. Biol. Chem. 262:5769-5774, 1987
and Kanda, P., Kennedy, R.C., and Sparrow, J.T. Synthesis of Polyamide
Supports for Use in Peptide Synthesis and as Peptide-resin Conjugates for
Antibody Production. Int. J. Peptide Prot. Res. 38:385-391, 1991.
Jim Sparrow
-------------------------------------------------------
Dr. James T. Sparrow
Dept. of Medicine
Baylor College of Medicine
One Baylor Plaza
Houston, TX 77030
Phone: 713 798-4156
FAX: 713 798-4121
email: jsparrow@bcm.tmc.edu
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From: abrf-request
To: Recipients of ABRF List
Subject: Peptide synthesis
Date: Tuesday, January 21, 1997 3:28PM
Sheppard et al in 1988 designed acid-degradable ketal linker for their
dimethylacrylamide/kieselgur resin.
This allows to prepare soluble immunogenic peptides attached to non-
immunogenic polyacrylamide carrier.
The question is who can arrange this kind of service?
Best wishes,
Slava