From: "Ken Taylor" <KTAYLO@scri.sari.ac.uk>
Date: Thu, 23 Jan 1997 11:10:38 GMT
Subject: pepsyn on acrylamide resin
To: Recipients of ABRF List <abrf@aecom.yu.edu>
>Sheppard et al in 1988 designed acid-degradable ketal linker for
>their dimethylacrylamide/kieselgur resin.
>
>This allows to prepare soluble immunogenic peptides attached to non-
>immunogenic polyacrylamide carrier.
>
>The question is who can arrange this kind of service?
>
>Best wishes,
>
>Slava
Hi there,
just a quick query. Do you really need the peptide on
acrylamide? Since this type of resin appears difficult to get hold
of, could you consider polyethylene glycol as a non-toxic, non-
immunogenic carrier? This is achieved by synthesising on TentaGel
type resins. Alternatively what about Multiple Antigenic peptides,
non-immunogenic lysine core and (usually) completely soluble.
Just a thought.
Ken.
Ken Taylor.
Peptide and DNA Services.
Scottish Crop Research Institute, Invergowrie, Dundee.
Phone 01382 56 27 31 Fax 01382 56 24 26
WWW URL http://www.scri.sari.ac.uk/