Re: volatile ion exch. mobile phase

Bill (chestnut@intrex.net)
Fri, 12 Sep 1997 07:20:29 -0400

David A. Schooley noted:

> TFA must
>also form a high-boiling azeotrope with water as 0.1% TFA becomes more
>concentrated as you evaporate it, as noted earlier today by Andy Alpert.

I would like to know more about this idea, because the experience of some
colleagues points toward TFA (0.05% - 0.2%) "evaporating" from ACN:H2O
mixes. Are both a possibility, or is there some study that can clarify this
issue?

Bill Chestnut
Pharmaceutical Sciences
Campbell University
Buies Creek NC