Richard Laursen
-----------------------------------------
>Dear Ms. Thyboll:
>
>1. I think one should be careful not to overreact to a situation. DIC is
>certainly a good reagent, introduced because it has properties (the
>dialkylurea is soluble) that are different than those of DCC. The reality is
>you should not spill the bottle on the bench or floor. This is the same
>thing that one should not do with many other reagents that are in common use.
>
>2. The hazards of skin sensitivity, dermatitis and allergic reactions are
>DEFINITELY associated with the use/contact with DCC - dicyclohexylcarbodiimide.
>However, I was not aware that this holds for DIC also. I ask Richard
>Laursen if he is certain of his statement, so that we can all be sure about
>what we are dealing with.
>
>Sincerely yours. NLB.
>
>>
>At 08:53 AM 98/1/15 +0100, you wrote:
>>Dear Mr Benoiton!
>>
>>Thank you for your answer concerning DIC.
>>I have heard the bad things about DIC and I
>>deliberate with myself about wether I am going
>>to work with it or not. I have been thinking of
>>maby using HBTU/HOBT/DIEA instead.
>>Your information further confirm what I have feared.
>>Thank you once more.
>>
>>Yours Sincerely
>>Maria Thyboll
>>Maria Thyboll
>>Department of Analytical Chemistry
>>Royal Institute of Technology
>>Teknikringen 36
>>100 44 Stockholm
>>SWEDEN
>>Tel +46 8 7906410
>>Fax + 46 8 108425
>>Email k93_mtl@k.kth.se
>>
>N. Leo Benoiton
>Department of Biochemistry
>University of Ottawa
>Ottawa, Ontario, Canada K1H 8M5
>Tel: 613 562 5800, Ext. 8216
>Fax: 613 562 5440
>eMail: benoiton@uottawa.ca
Richard A. Laursen
Department of Chemistry
Boston University
590 Commonwealth Ave.
Boston, MA 02215
Tel (617) 353-2491; FAX (617) 353-6466
email: <laursen@bu.edu>