Misc. - Storage if Iodoacetamide/Iodoacetic Acid

Ken Mitchelhill (k.mitchelhill@medicine.unimelb.edu.au)
Thu, 22 Jan 1998 12:24:44 +1100


Dear ABRF Colleagues,

I am curious to hear how various labs approach the storage of Iodoacetamide
or Iodoacetic acid?

In the past, we have been careful to purge bottles of these compounds with
inert gasses each time we use them and store them in the dark at
refigerator or freezer temperatures. We still however only get a pretty
short lifetime out of each container before it starts turning yellow. I am
loath to use either of these compounds after they show this yellow
decomposition color because I have been told that this represents free
Iodine which can result in undesired oxidations or iodinations.

Am I being too cautious in this regard or can any of you recommend a better
way of handling these compounds?

Ken

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Ken I. Mitchelhill
The John Holt Protein Structure Laboratory
St. Vincent's Institute of Medical Research
41 Victoria Parade
Fitzroy 3065 Victoria
AUSTRALIA

Telephone: 61-3-9288 2480
Facsimile: 61-3-9416 2676

Email: k.mitchelhill@medicine.unimelb.edu.au

Laboratory: http://www.medstv.unimelb.edu.au/WWWDOCS/SVIMRdocs/JHPSL.html
ABRF: http://www.medstv.unimelb.edu.au/abrf.html

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