Peptide counterions and biological activity

Jean Lucchetti (j.lucchetti@eurogentec.be)
Mon, 16 Feb 1998 11:46:12 -0800

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Usually after HPLC purification of our peptides we end with TFA salts. I
wonder if using these peptides as they are instead of the corresponding
acetate or hydrochloride can lead to significant modifications of the
response in biological assays like for instance receptor stimulation?
I'd appreciate any comments or references. Thanks,

-- 
Jean LUCCHETTI, Ph.D.
EUROGENTEC Bel S.A.
Parc de Recherche Cense Rouge
B-4102 SERAING (BELGIUM)
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E-mail : <mailto:j.lucchetti@eurogentec.be>
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