Re: Synthesize a peptide with phosphated serine

Michael Johns (JohnsM@em.agr.ca)
Thu, 19 Mar 1998 12:44:49 -0500

Michael Johns
Lacombe Research Centre
Lacombe, Alberta
T4L 1W1
Canada

Tel: 403-782-8100 ext 268
Fax: 403-782-6120

>>> Bao-Shiang Lee <boblee@uic.edu> 03/18 2:00 PM >>>
Hi everyone, I need to make a peptide with phosphated serine.
Please give me some advice, sources of the materials (prices) and
protocols. Best wishes. Bob

I have made a variety of phosphoserine derivatives with different phosphate protecting groups. Here are some papers:

Synthesis of Oligophosphoseryl sequences occurring in casein, Int. J. Peptide Res., 36, 1990, 97-103

Further studies on the use of 2,2,2-trichoroethyl groups for the phosphate protection in phosphoserine syntheses, Int. J. Peptide Res. 39, 1992, 82-86

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