RE: Ethylenimine

Robert Moritz (uunet!mail.uu.net!uunet!ludwig.edu.au!Robert.Moritz@mail.uu.net)
Wed, 1 Apr 1998 12:57:34 +1000

Dear Lowell,
Serva (purchased by Boehringer-Ingelheim) still sells Ethylenimine
under the name Aziridine. You can only buy this in bulk and it must be
shipped due to its toxicity (usually in a steel drum chained to the front of
the ship!) I don't know of a distributor in the US (being from the land of
OZ) but the German phone and fax are +6221-5020 and +6221-502113
respectively

Best regards,

Robert Moritz.

Robert Moritz
Chief Research Officer,
Joint Protein Structure Laboratory
Ludwig Institute For Cancer Research &
The Walter and Eliza Hall Institute of Medical Research
Royal Melbourne Hospital, Parkville,
Victoria, Australia 3050
Phn +61-3-9341-3155, Fax +61-3-9341-3192
Email: Robert.Moritz@ludwig.edu.au or Moritz@wehi.edu.au

> -----Original Message-----
> From: L. Ericsson [SMTP:ericsson@u.washington.edu]
> Sent: Wednesday, 1 April 1998 9:15
> To: Robert Moritz
> Subject: Ethylenimine
>
>
> Does anybody know where I can buy, beg, or steal this compound. It is
> very toxic, has not been used much so most distributors have discontinued
> carrying it. It can be used to alkylate cysteine which then can be
> cleaved by trypsin or lys-C.
>
> Ref. Methods in Enzymology Vol 11 pg 315-317 (1967) Article on
> S-aminoethylation by David Cole.
>
> -Lowell H. Ericsson, Dept. of Biochemistry, U. of Washington, Seattle, WA
> phone 206-543-5320 FAX 206-685-1792
>
>