Psyn:Synthesis on side chain of Asp

SSPEQ (SSPEQ@crchul.ulaval.ca)
Thu, 9 Jul 1998 14:02:27 +0500

Hi everyone,

I need to synthesize a tetrapeptide with Asp at the third position and Ser
on the side chain of Asp. (Ser being the fourth amino acid of the
tetramer). I just want to verify this: Is this right to use the
Fmoc-Asp-OtBu (#04-12-1080 from Novabiochem) which has its alpha-carboxy
blocked and its side chain carboxy unblocked.

Is there an other derivatives that would be better?

Thank you very much for your help,

Sylvie

Sylvie Bourassa Ph.D.
Service de Sequence de Peptides de l'Est du Quebec (SSPEQ)
CHUL Research Center Room 9750
2705, Laurier blvd
Ste-Foy, Quebec
Canada G1V 4G2
phone 418 656-4141 ext 7088
fax 418 654-2159
Email: sspeq@crchul.ulaval.ca