Endoproteinase Glu-C

Christoph Turck (turck@itsa.ucsf.edu)
Thu, 13 Aug 1998 08:44:10 -0700 (PDT)

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Does anybody know if Endoproteinase Glu-C (EC 3.4.21.19) will cleave
after glutamic acid residues that are flanked by phosphotyrosine on either
side (...-pY-E-... or ...-E-pY-...)? We are using the enzyme for mapping
tyrosine phosphorylation sites by radioactive Edman degradation.

Thanks,

Chris (turck@itsa.ucsf.edu)

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