Mukaiyama peptide synthesis is effectively a dehydratation reaction and
formal donors of HO- (COOH) and H- (NH2) are essentially required.
Therefore (if I have understood your question correctly), R-COOSu will not
work instead of R-COOH with Mukaiyama reagents.
However, R-COOSu will react with majority of amino groups as such. In case
of problems add 0.1 eq of 4-(dimethylamino)pyridine (provided that
studying of the Mukaiyama reaction is not your ultimate goal).
Kindest regards,
Igor
Laboratory of Peptide Chemistry
Branch of Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry
Pushchino, Moscow Region
142292, Russian Federation
E-mail: <rodionov@fibkh.serpukhov.su> or <Igor_Rodionov@iname.com>
Fax: (0967)-79-05-27
Phones: (0967) 73 54 42; private: (0967) 73 58 26