Peptide synthesis problems.

Terry Stoming (tstoming@MAIL.MCG.EDU)
Mon, 05 Oct 1998 08:00:07 -0400

Item Type: Task
Start Date: 10/05/1998 (Monday)
Due: 10/05/1998 (Monday)

We have synthesized a small 9-mer with 1-trp,3-arg,1-tyr, 1-thr, 1-ala. 1-ile, and an N-term ser. We did Fmoc on for the N-term serind and removed it later after cleavage from the resin. The calculated mw is 1208.39. Our mass spec (ion spray) shows a molecular ion at 1220 with a nice 610 peak too. What in the world could have a mw difference of 12???