My previous posting of the preliminary schedule for the ABRF '99 had an insertion mutation that duplicated the schedule at the end of the tutorial session. Please accept my apologies. I hope the revised version posted here is not similarly replicated. I have added a few titles that I received since posting the schedule yesterday. remember that registration details and elctronic submission forms for abstracts can be found at http://www.faseb.org/meetings/abrf99/preprog.html.
Sorry for the confusion.
Mark Lively
>>>>>> Preliminary Schedule (Revised 4 December 1998)<<<<<<<
March 19-22, 1999
Durham Marriott at the Civic Center
Durham, North Carolina
Mark O. Lively and David Landsman, Organizers
PLENARY SESSIONS
Plenary Session 1: Genomes and Function
Chair: Kenneth A. Walsh (University of Washington, Seattle, WA)
Marco A. Marra, Ph.D. (Genome Sequencing Center, Washington University School of Medicine) "Caenorhabditis. elegans Genome Project."
Michael Y. Galperin (National Center for Biotechnology Information, NLM, NIH, Bethesda, MD) "Hits and misses in functional genomics: First lessons from a comparison of bacterial and archaeal protein sequences."
Plenary Session 2: Chromatin structure and gene regulation
Chair: David Landsman (National Center for Biotechnology Information, NLM, NIH, Bethesda, MD)
C. David Allis (University of Virginia, Charlottesville, Virginia) "Linking histone modifications to gene activation."
Alan P. Wolffe (NICHD, NIH, Bethesda, Maryland) "Linking histone modifications to gene repression."
ABRF Award Presentation
Awardee: Marvin H. Caruthers (University of Colorado, Boulder, CO) "Synthesis of Oligonucleotides and Oligonucleotide Analogs"
Plenary Session 3: New and Emerging Techniques in Structural Biology.
Chair: Paul Matsudaira (MIT, Boston, MA)
David C. Schwartz (New York University, New York, New York) "Optical Mapping: A New Approach for Whole Genome Analysis"
Joachim Frank (Wadsworth Center, Albany, NY) "Ribosome Structure and Function, as Explored by Three-Dimensional Cryo-Electron Microscopy."
SCIENTIFIC SESSIONS
(assigned by order of appearance in the schedule)
1. Bioinformatics: Macromolecular Structure Databases.
Chair/Speaker 1: Helen M. Berman (Rutgers University, Piscataway, NJ) "Our vision and implementation for the new PDB"
Speaker 2: Phil Bourne (U. C. San Diego, San Diego, CA) "PDB Live!"
2. Technological Advances: DNA Sequence Analysis.
Speaker 1/Chair: Paul Matsudaira (MIT, Boston, MA) " Ultrafast DNA Genotyping and Sequencing on Microfabricated Devices"
Speaker 2: Barry Karger (Northeastern University, Boston, MA) "Long DNA Reads by Capillary Electrophoresis."
Speaker 3: Rich Mathies (U.C. Berkeley, Berkeley, CA) "Integrated Micro-fabricated DNA Analysis Systems"
3. Functional Analysis: Gene Array Expression analysis.
Chair/Speaker 1: John Quackenbush. (The Institute for Genome Research, Rockville, MD) "Whole Genome Functional Analysis"
Speaker 2: Michael Bittner (NHGRI, NIH, Bethesda, MD) "Expression profiling, a first look at the cell as a system."
4. Technological Advances: Mass Spectrometry of Proteins.
Chair/Speaker 1: Karl Clauser (Millenium Pharmaceuticals, Inc. Cambridge, MA) "Using Automated LC/MS/MS on Digests of Complex Protein Mixtures. Can One Get Identities and Differences?"
Speaker 2: Rachel Ogorzalek Loo (Parke-Davis Pharmaceutical, Ann Arbor, MI) "Virtual 2D Gel Electrophoresis/Mass Spectrometry"
Speaker 3: TBN
5. Gene Identification: Identifying Gene Products and Protein Motifs.
Chair/Speaker 1: Andy Baxevanis (NHGRI, NIH Bethesda, MD) "Protein Sequence Analysis: BLAST and Beyond."
Speaker 2: Christopher W.V. Hogue (University of Toronto, Toronto, Canada) "Protein Structure Analysis: Databases, Visualization, and Prediction."
6. Bioinformatics: The Pyococcus furiosus Genome Project.
Chair/Speaker 1: Robert Weiss (University of Utah, Salt Lake City, UT)
Speaker 2: Dennis L. Maeder (University of Maryland Biotechnology Institute, Baltimore, MD)
7. Gene Identification: Gene Identification: Software Methods for Finding Genes in Large DNA Sequences.
Chair/Speaker 1: Warren Gish (Washington University, St. Louis, MO) Analysis and annotation of the human genome.
Speaker 2: Chris Burge (MIT, Cambridge, MA) Title: Reliable automatic annotation of genes in genomic sequences
8. Functional Analysis: Post-translational Modifications.
Chair/Speaker 1: Kenneth A. Walsh (Univ. Washington, Seattle) "The Need for Analysis of Post-Translational Modifications."
Speaker 2: Matt Posewitz (Sloan Kettering, New York, NY) "Isolation and Analysis of Phosphopeptides."
Speaker 3: Hsien Lu "Analysis of Complex Disulfide Bridges by Mass Spectrometry in Conjunction with Chemical Methods."
9. Technological Advances: Recent Advances in Synthetic Protein Construction and Utility.
Chair/Speaker 1: Gregg Fields (Florida Atlantic University, Boca Raton, FL) "Are There Simple Methods for Creating Protein-Like Architectures?"
Speaker 2: Kevin H. Mayo (University of Minnesota, Minneapolis, MN) " Designing Beta-sheet-forming Peptides."
10. Gene Identification: Comprehensive Gene Mapping and Single Nucleotide Polymorphisms.
Chair/Speaker 1: Tara Matise, (The Rockefeller University, New York, NY) "Construction of dynamic chromosome maps"
Speaker 2: David G. Wang (Bristol-Myers Squibb Company, Hopewell, NY) "Large-scale identification, mapping and genotyping of single nucleotide polymorphisms in the human genome."
11. Bioinformatics: Database Design and Sequence Annotation.
Chair/Speaker 1: B. F. Francis Ouellette (University of British Columbia, Vancouver, B.C.) "GenBank"
Speaker 2: Ilene Mizrachi (NCBI,NLM, NIH, Bethesda, MD) "Data flow at NCBI"
12. Functional Analysis: Protein Identification Using Mass Spectrometry.
Chair: John Stults (Genentech, South San Francisco, CA)
Speaker 1: Leigh Anderson (Large Scale Biology Corp., Rockville, MD)
Speaker 2: Hanno Langen (F. Hoffman-La Roche AG, Basel, Switzerland)
Speaker 3: Ruedi Aebersold (University of Washington, Seattle, WA)
TUTORIALS
(assigned by order of appearance in the schedule)
1. Bioinformatics and Education.
Chair/Speaker 1: Chuck Staben, (Univ. of Kentucky, Lexington, KY) Genomics and Bioinformatics Instruction Status, Needs, and Initiatives
Speaker 2: Donald O. Natvig (University of New Mexico, Albuquerque, NM) The Neurospora Genome Project at the University of New Mexico
2. Practical Uses of Internet Tools.
Chair: Ken Mitchelhill (St. Vincents Inst. Medical Research, Victoria, Australia)
Speakers: [needs internet access via T1]
Speaker 1: Johanna McEntyre (National Center for Biotechnology Information, NLM, NIH, Bethesda, MD) "PubMed"
Speaker 2: Ken I. Mitchelhill (The John Holt Protein Structure Laboratory, St. Vincent's Institute of Medical Research, Victoria, AUSTRALIA) "Sequence Database Searching Using Short Query Sequences"
Speaker 3: Richard S. Johnson (Immunex, Seattle, WA) "Internet Tools for the Analysis of Mass Spectrometry Data"
3. Genotyping in a Shared Facility.
Chair/Speaker 1: Duane Bartley (Johns Hopkins Medical Institute, Baltimore, MD) "Fragment Analysis: It's Not Just For Genotyping Anymore."
Speaker 2: Linda W. Ballard (University of Utah, Salt Lake City, UT) "Genotyping: Real Projects, Real Problems."
4. DNA Sequence Analysis in a Core Laboratory.
Chair/Speaker: Theodore W. Thannhauser (Cornell University, Ithaca, NY) "DNA Sequencing in a Multi User Core Facility: Automating the Process"
Speakers: George S. Grills (Albert Einstein College of Medicine, Bronx, NY) "An Analysis of Methods for Optimizing DNA Sequencing Quality and Throughput"
5. Characterization of Biotechnology Pharmaceuticals.
Chair/Speaker 1: Elizabeth Fowler (Autoimmune, Inc., Lexington, MA) Aspects to consider in characterizing biopharmaceutical proteins."
Speaker 2: Eric W. Kuhn (AutoImmune, Inc., Lexington, MA) "Characterization of collagen, a natural product biopharmaceutical."
Speaker 3: Kalyan Anumulan (SmithKline Beecham, King of Prussia, PA) "Approaches to characterization of the carbohydrate moieties of glycoproteins."
6. Practical Aspects of Mass Spectrometry.
Chair/Speaker 1: Roland Annan (SmithKline Beecham Pharmaceuticals, King of Prussia, PA) "Data acquisition considerations for obtaining meaningful mass spectra"
Speaker 2: Paul Tempst (Memorial Sloan-Kettering Cancer Center, New York, NY) "Practical Sample Preparation for Mass Spectrometry"
7. Implementing Genechip Microarray Technologies in Facility Laboratories.
Chair/Speaker 1: George Grills (Albert Einstein College of Medicine, Bronx, NY) "Problems and Pleasures of Implementing Microarray Technologies"
Speaker 2: Aldo B. Massimi (Albert Einstein College of Medicine, Bronx. NY) "Implementation of a Custom cDNA Microarray Facility at the Albert Einstein College of Medicine."
Speaker 3: Hans Albertsen (University of Utah, Salt Lake City, UT) "Implementing a Microarray Facility: A Retrospective View of the Experience at the Huntsman Cancer Institute."
Speaker 4: Chandi Griffin (University of California San Francisco, San Francisco, CA) "GeneChip Microarrays in a Clinical Core Facility: Practical Considerations"
Discussion Period: George S. Grills, Aldo B. Massimi, Hans Albertsen, Chandi Griffin.
8. Protein Identification in Gels and Data Handling.
Chair: Len Packman (University of Cambridge, Cambridge, UK)
Speaker 1: Scott D. Patterson (Amgen Inc., Thousand Oaks, CA) "Experiences with the use of the LCQ ion trap mass spectrometer for protein identification."
Speaker 2: "Len C. Packman (University of Cambridge, Cambridge, UK) "Browsing MS data - compiling results and sharing information through a Web-based electronic notebook."
9. Integration of Bioinformatics and the Chemistry Shared Resource.
Chair/Speaker 1: Clayton Naeve (St. Jude Children's Hospital, Memphis, TN) "Integrating bioinformatics and the chemistry shared resource."
Speaker 2: E. A. Greene and Mary Kay Dolejsi (Fred Hutchinson Cancer Research Center, Seattle, WA) "It flows both ways: how the chemistry core informs bioinformatics."
RESEARCH COMMITTEE PRESENTATIONS
Saturday 2:00 - 3:00
Committee Session 1: Nucleic Acids & DNA Sequencing
Committee Session 2: Protein Sequence & Internal Protein Sequence
Committee Session 3: Survey Committee
Monday 2:00-3:00
Committee Session 4: Fragment Analysis & Peptide Synthesis
Committee Session 5: Mass Spectrometry & Q and C
Committee Session 6: Education