Biotin Sulfoxide

Singleton, David H (david_h_singleton@groton.pfizer.com)
Fri, 4 Dec 1998 15:54:31 -0500

Much to my chagrin, I biotinylated a compound with a 50/50 mixture of biotin
and biotin sulfoxide. (Warning: The mixture came from the starting biotin
reagent. You might want to do QC here.)

Has anyone successfully reduced the sulfoxide?

I never had much success with Met(O) to Met, so I doubt this is easily
rescued.

David H. Singleton