monosaccharide analysis

Joseph Zaia (jzaia@osiristx.com)
Wed, 3 Mar 1999 11:06:23 -0500

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To the ABRF:

In March, 1997, the ABRF Carbohydrate Analysis Research Committee reported
on quantitative monosaccharide analysis. The conclusion was that both
HPAE-PAD and GC-MS methods for monosaccharide analysis showed high
variability. Is there any development in identifying the sources of error
in monosaccharide analysis? Much of the study was done using Dionex
equipment, so perhaps a representative of that company will comment. It
would also be helpful to hear from laboratories who routinely run these
analyses to see if there is a consensus.

Thanks in advance.

Joe Zaia

Osiris Therapeutics, Inc
2001 Aliceanna St.
Baltimore, MD 21231-2001
Phone: 410-522-5005 X 297
Fax: 410-522-6999

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monosaccharide analysis

To the ABRF:

In March, 1997, the ABRF Carbohydrate = Analysis Research Committee reported on quantitative monosaccharide = analysis.  The conclusion was that both HPAE-PAD and GC-MS methods = for monosaccharide analysis showed high variability.  Is there any = development in identifying the sources of error in monosaccharide = analysis?  Much of the study was done using Dionex equipment, so = perhaps a representative of that company will comment.  It would = also be helpful to hear from laboratories who routinely run these = analyses to see if there is a consensus.

Thanks in advance.

Joe Zaia


Osiris Therapeutics, Inc
2001 Aliceanna St.
Baltimore, MD = 21231-2001
Phone: 410-522-5005 X = 297
Fax:       410-522-6999

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