Re: prediction methods

Rolando Rodriguez (rolando@antares.cigb.edu.cu)
Thu, 04 Mar 1999 14:18:09 -0500

Hi,

Would you clarify some points on your problem, I can not fully
understand which is your starting point, what do you expect at
the end and which programs do you use.

Are you searching for peptides to generate specific antibodies ?

An algorithm to combine the two programs would be easier to
write than a combined one.

Best regards,

Rolando Rodriguez,
Head, Protein Structure and Design,
Division of Physical Chemistry,
CIGB, Havana, Cuba.

email: Rolando.Rodriguez@cigb.edu.cu
Rolando.Rodriguez@EMBL-Heidelberg.de

--

david andreu wrote: > > Hi, > > Does anyone know of an algorithm that can do both sequence homology and > antigenicity predictions? > This would come in handy when a user wants an antibody that distinguishes best > among several fairly homologous forms of a protein. So far, the way I go about > this is to run the relevant sequences through both types of algorithms and > then compare (by hand, so to say). When the number of homologous sequences is > large this becomes a bit complex. What I am looking for is an integrated > program that does both things simultaneously. Any suggestions? Thanks in > advance. Regards, > > > David Andreu > >