Issues:
1) The 1100 and 1050 have a top flow rate of 10 mL/min which limits the size
of column you can use. Our biggest column is 22 mm O.D. and we have to
operate at the lower end of the flow range.
2) Faulty parts have been a problem. Outlet valves have been a gamble: some
work, some don't. HP maintains culpable deniability but your service
engineer can set you straight. After a trouble-filled setup due to faulty
boards and incompatibilities with a non-HP computer, the machine has run
without problems.
3) Service: After one unsatisfactory service engineer, I've had two
excellent ones.
4) I'm not happy with some of their service. Apparently, HP has outsourced
the first line of defense: troubleshooting over the phone. My experience
has been that the folks who answer the phone are being timed and the user is
presumed to have screwed up.
In summary, the HP1100 is a very good machine for analytical work.
Dr. Jim Farmar, Director
MicroChemistry/Kimball Research Institute/NYBC
212 570-3128
-----Original Message-----
From: Association of Biomolecular Resource Facilities
[mailto:abrf-request@aecom.yu.edu]On Behalf Of Michael A Imbalzano
Sent: Wednesday, April 14, 1999 3:24 PM
To: Recipients of ABRF List
Subject: HPLC systems
I plan to buy a new HPLC system to be used primarily for
synthetic oligo purification. I've been looking at systems from
Beckman, Waters, and HP. I was wondering if anyone had any comments
(good or bad) about the equipment they are currently using.
I am particularly interested in feedback on the HP1100.
I was recently told that they are not reliable.
Thanks so much,
Mike