phenylglyoxal modification of ARGININE

Suzanne Perry-Riehm (perry@interchange.ubc.ca)
Fri, 7 May 1999 15:40:26 -0700 (PDT)

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I have a client who let me know ( belatedly) that he has modified his
arginines with phenylglyoxal which supposedly forms a cyclic derivative of
the ARG sidechain. This was performed prior to alpha-chymotrypsin
digestion. I have already performed N-terminal sequencing on the peptide
but am curious to know if anyone has an idea where this might elute ( or
co-elute)?

Thanks for your answers in advance!
Suzanne Perry-Riehm

Suzanne C. Perry, Research Associate
NAPS Protein Sequencing and Peptide Mapping Laboratory
Biotechnology Department, University of British Columbia
CANADA
phone:(604)822-9688( direct) or (604)822-9662 (main) Fax:(604)822-0676
email:perry@interchange.ubc.ca
Visit our web page at : www.biotech.ubc.ca/naps/napshome.htm

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