I heard Fmoc chemical ligation rumors at the APS meeting in Minneapolis. The
following references were furnished. I haven't tracked them down yet, so I'm not
sure how helpful they'll be. I'm also not certain whether they address native
chemical ligation.
Tet. Lett. vol 39, p8669, 1998
Chem. Lett. p1157, 1997
Good luck.
Jeni
Responding to the message of <3.0.32.19990713152234.0069ac20@tigger.cc.uic.edu>
from Bob Lee <boblee@uic.edu>:
>
> Hi everyone,
>
> I am looking into using the native chemical ligation to synthesize big
> peptides. The strategy is all base on the Boc chemistry. Can that strategy
> be used in Fmoc chemistry? Any references or suggestions would be
> appreciated.
>
> Bob Lee
>
> .
Janelle Lauer-Fields
Department of Chemistry & Biochemistry
Florida Atlantic University
777 Glades Road
Boca Raton, Florida 33431
561-297-2094/Fax 561-297-2759