I'd like to point out that non-porous materials aren't the only option. We
have demonstrated HPLC as both sizing and DHPLC applications on a Wide Pore
Silica based material. Porous materials have the advantage of high sample
capacity for semipreparative work. This is marketted by HP as Eclipse
dsDNA. LEt me know if you have any other questions.
Alex Apffel, Ph.D.
Biomeasurements Group
Hewlett-Packard Laboratories
3500 Deer Creek Road
Palo Alto, CA 94304
Tel: 650-857-6090
Fax: 650-852-8502
Email: alex_apffel@hpl.hp.com
-----Original Message-----
From: Gordon Alton [mailto:galton@signalpharm.com]
Sent: Friday, August 06, 1999 7:08 PM
To: Recipients of ABRF List
Subject: DNA/RNA chromatography
Dear ABRFers,
Does anyone have experience with DNA or RNA chromatography on non-porous
reverse phase resin? Which chromatography companies have this type of resin?
I would greatly appreciate any information. In advance, thanks.
--------------------------------------------------------
Gordon Alton, PhD
Gene and Protein Discovery Group
Signal Pharmaceuticals Inc.
5555 Oberlin Drive
San Diego, CA 92121
Email: galton@signalpharm.com
Phone: 619-558-7500 x8252
Fax: 619-623-0870
WWW: http://www.signalpharm.com
-------------------------------------------------