FW: N terminal serine

Everson, Anita [PRI] (AEverson@prius.jnj.com)
Fri, 13 Aug 1999 13:06:48 -0400

Try DMSO or NMP. Also, the piperidine helps a lot to get it to go in. If
it still doesn't go in after the addition of the pip try adding more
solvent/ warm bath/ time. Good luck!

Anita Everson
Peptide Lab
RW Johnson PRI, La Jolla, CA

> -----Original Message-----
> From: Terry Stoming [SMTP:TSTOMING@MAIL.MCG.EDU]
> Sent: Friday, August 13, 1999 2:53 AM
> To: Recipients of ABRF List
> Subject: N terminal serine
>
> I have recently made a peptide containing an N-terminal serine. Left the
> Fmoc on and purified it, including lyophylization. It seems reluctant to
> go into DMF so I can cleave the Fmoc. Does anyone have any suggestions???