RE: AAA

Breslav, Michael [PRI] (MBreslav@prius.jnj.com)
Fri, 13 Aug 1999 19:23:34 -0400

I had the same problem, asked abrf a few weeks ago, and got offers from
Japan and Australia only.
However I solved this problem in my own lab using HPLC method including
ChiralTech's CR+ column with a perchloric acid containing mobile phase after
hydrolysis of the peptide with HCl. Many, if not all D/L amino acids can be
resolved. You may want to contact Chiral Technologies tel.800-624-4725.
Regards,
Michael Breslav
R.W.Johnson PRI
Spring House, PA

> -----Original Message-----
> From: MCNEMAR, CHARLES [SMTP:CHARLES.MCNEMAR@spcorp.com]
> Sent: Friday, August 13, 1999 10:10 AM
> To: Recipients of ABRF List
> Subject: RE: AAA
>
> Is there a service that can determine D/L conformation of amino acids? We
> have
> an N-terminally blocked tripeptide of known sequence and would like to
> know
> the
> conformation of a valine.
>
> Charles McNemar, Ph.D.
> Associate Principal Scientist
> Schering-Plough Research Institute
> 2015 Galloping Hill Road
> Kenilworth, NJ 08829
> 908-740-7194
> FAX: 908-740-4844
> charles.mcnemar@spcorp.com