Re: peptide + mass 40

Matteo Villain (villain@uab.edu)
Thu, 09 Sep 1999 13:43:02 -0500

Dear Gautam, just a curiosity, what was the second peak, and which protecting group
you used for K, S, and aldo, it was exactely 40 or it was 42 ?
Bye

gsarath@unlnotes.unl.edu wrote:

> Dear All: I recently synthesized a 17 mer (1R, 3K, 3Y, 1D, 2E, 1S, 1T, 1N, 1P,
> 2V, 1A), acetylated at the N-terminus using acetylimidazole, C-terminus was
> amidated. Synthesis looked normal, as did the yields of the crude peptide.
> Analytical HPLC showed two close peaks, I took the major one to be N-blocked (it
> was). However, the mass is +40 of the expected, any ideas?? Thanks in advance
> for the wisdom, Gautam Sarath

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Matteo Villain                   E-mail : villain@uab.edu
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