modified aa's for pep syn

alex bell (ehjb@musica.mcgill.ca)
Thu, 9 Sep 1999 21:31:46 -0400

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Dear Peptide Synthesizers,

I would like to know if the following modified amino acids are =
commercially available and if synthesis becomes problematic at the =
indicated positions?=20

alaninal-semicarbazone; phenylalaninal-semicarbazone (C-terminus)

difluro(phosphono)methyl-phenylalanine=3DX (internal: ...DXXR...; =
...EXXLc-terminus, where D=3Dasp,E=3Dglu,R=3Darg,L=3Dleu)

N-t-butyloxycarbonyl-tyrosyl (N-terminus)

Thank you in advance,
alex
Alexander W. Bell

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Dear Peptide Synthesizers,
 
I would like to know if the following modified = amino=20 acids are commercially available and if synthesis becomes = problematic at=20 the indicated positions?
 
alaninal-semicarbazone; phenylalaninal-semicarbazone = (C-terminus)
 
difluro(phosphono)methyl-phenylalanine=3DX = (internal:=20 ...DXXR...; ...EXXLc-terminus, where = D=3Dasp,E=3Dglu,R=3Darg,L=3Dleu)
 
N-t-butyloxycarbonyl-tyrosyl = (N-terminus)
 
Thank you in advance,
    alex
Alexander W. Bell
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