At 3:54 PM +0000 10/4/99, Len Packman wrote:
>Dear ABRFers (especially the chemist ones)
>
>I can't find para-iodosobenozoic acid in Aldrich, only the 2- (ortho-) form.
>I also do not understand the mechanism of action and the use of the term
>1-iodoiodoxolin-3-one in Ron's subject line. I have been unable to contact
>him at beavis@proteometrics.com to get clarification and no literature
>searches have helped.
Len-
looks like you got some misdirections here. What you want is
INDEED the ortho isomer. No, I have never used it, but considered
it. Seems to be a standard method- see p. 102-103 of this reference
for conditions and reaction mechanism:
Allen G. (1989) Sequencing of Proteins and Peptides. Second ed.
Edited by Burdon R. H. and van Knippenberg P. H. Laboratory
Techniques in Biochemistry and Molecular Biology. Elsevier, Amsterdam
David
David A. Schooley
Dept. of Biochemistry/330
Univ. of Nevada
Reno, NV 89557
schooley@unr.edu
tel: (775) 784-4136; fax (775) 784-1419
NOTE NEW AREA CODE: Mandatory after 5/15/99
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Content-Type: text/enriched; charset="us-ascii"
<fontfamily><param>Geneva</param>At 3:54 PM +0000 10/4/99, Len Packman
wrote:
<excerpt>Dear ABRFers (especially the chemist ones)
I can't find para-iodosobenozoic acid in Aldrich, only the 2- (ortho-)
form.
I also do not understand the mechanism of action and the use of the
term
1-iodoiodoxolin-3-one in Ron's subject line. I have been unable to
contact
him at beavis@proteometrics.com to get clarification and no literature
searches have helped.
</excerpt>
Len-
looks like you got some misdirections here. What you want is INDEED
the ortho isomer. No, I have never used it, but considered it. Seems
to be a standard method- see p. 102-103 of this reference for
conditions and reaction mechanism:
Allen G. (1989) Sequencing of Proteins and Peptides. Second ed. Edited
by Burdon R. H. and van Knippenberg P. H. Laboratory Techniques in
Biochemistry and Molecular Biology. Elsevier, Amsterdam
David
</fontfamily>
David A. Schooley
Dept. of Biochemistry/330
Univ. of Nevada
Reno, NV 89557
schooley@unr.edu
tel: (775) 784-4136; fax (775) 784-1419
NOTE NEW AREA CODE: Mandatory after 5/15/99
--============_-1273041357==_ma============--