peptide synthesis

Amanda Hall (mbah@mail.newcastle.edu.au)
Wed, 03 Nov 1999 08:45:47 +1100

Hi everyone,

A question for the peptide synthesis people. I have just sequenced a
peptide that has an amino group at the C-terminal end rather than the
normal carboxy group. What difference does this make to the molecular
weight of the peptide. Is it just a matter of subtracting the COOH and
adding the NH2 or does the NH2 attach to the C-terminal end through the
normal loss of water, or some other mechanism?

Thanks alot

Amanda Hall

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Amanda Hall (BSc. Hons)
Professional Officer
Newcastle Protein
University of Newcastle

ph 02 4921 7299
fax 02 4921 6903
email: mbah@mail.newcastle.edu.au
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