Re: MS and drug discovery

Paul Murphy (paul.v.murphy@ucd.ie)
Fri, 05 Nov 1999 18:26:11 -0500

> Can MS be used to screen any of the following assays?:
> protein-protein
> protein-peptide
> protein-small molecule
> nucleic acid-protein
> nucleic acid peptide
> nucleic acid small molecule
>

There was a paper I remember looking at in Chemistry and Biology
last year or the year before where MS was used in enzyme assay
using an automated MS instrument and with internal standard
quantitation method.
If I remember rightly the work was published by C.-H. Wong and
co-workers at Scripps in California.

Sorry that I dont have the precise reference.

Paul Murphy