Re: PEPSYN: dipeptide with reduced peptide bond
Alfred Chung (achung@biotech.ufl.edu)
Thu, 11 Nov 1999 11:16:02 -0500 (EST)
At 09:23 AM 11/10/99 -0600, Henriette Remmer wrote:
>
>Dear all:
>
>I was asked to synthesize a peptide containing a reduced peptide bond.
>Are Fmoc-protected dipeptides containing a reduced peptide bond
>commercially available? If yes, where?
>Specifically I am looking for Fmoc-PheCH2NHArg-OH.
>
>Thanks!
>Henriette
>
>Henriette A. Remmer, Ph.D
>Director
>Protein Sciences Facility
>Biotechnology Center
>University of Illinois
>311/315 Noyes Laboratory, Box 62-1
>505 S. Mathews Ave.
>Urbana,IL 61801
>Tel: (217) 333-4695 (Lab) (217) 333-3841 (office)
>Fax: (217) 244-1142
>homepage: http://www.life.uiuc/biotech/protein_sc.html
>-------------------------------------
>
> I do not think you could obtain the reduced peptide bond dipeptide in
commerical source. I do think you will have better luck in Boc chemistry or
the combination of Boc and Fmoc chemistry.
>