Modification of tyrosine by the iodogen method

Brett Phinney (phinney@unity.ncsu.edu)
Sun, 21 Nov 1999 15:18:13 -0500

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Hi, I was wondering if anyone knows of any rules concerning iodinating =
tyrosine by the iodogen method. Specifically, will a tyrosine always be =
iodinated multiple times if there is an excess of activated iodine over =
tyrosine residues? Conversely, is it possible for a tyrosine to be =
modified only once in the presence of excess activated iodine?

Thanks in advance for the info.

--------------------------
Brett Phinney
Department of Biochemistry
North Carolina State University
ph# 919-515-5786 fax# 919-515-2047

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Hi, I was wondering if anyone knows of any rules = concerning=20 iodinating tyrosine by the iodogen method. Specifically, will a = tyrosine=20 always be iodinated multiple times if there is an excess of activated = iodine=20 over tyrosine residues? Conversely, is it possible for a = tyrosine to=20 be modified only once in the presence of excess activated = iodine?
 
 
Thanks in advance for the info.
 
 
--------------------------
Brett Phinney
Department of Biochemistry
North Carolina State University
ph# 919-515-5786 fax# 919-515-2047
 
 
 
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