ABRF : Delta Mass

Delta Mass
A Database of Protein Post Translational Modifications

Avg.Mass Change	Modification

-79	5' dephospho
-58	Desmosine (from Lysine)
-48	decomposed carboxymethylated Methionine
-44	decarboxylation of gamma carboxy Glutamate
-43	gamma-glutamyl semialdehyde (from arginine)
-42	Ornithine (from Arginine)
-34	Lysinoalanine (from Cysteine)
-34	Lanthionine (from Cysteine)
-34	Dehydroalanine (from Cysteine)
-30	Homoserine formed from Met by CNBr treatment
-27	Oxidation of arginine (to glutamic acid)
-18	Formylglycine (from cysteine)
-18	Pyroglutamic Acid formed from Glutamic Acid
-18	Dehydration (-H2O)
-18	S-gamma-Glutamyl (crosslinked to Cysteine)
-18	O-gamma-Glutamyl- (Crosslink to Serine)
-18	Serine to Dehydroalanine
-18	Alaninohistidine (Serine crosslinked to theta or pi carbon of Histidine)
-18	Misincorporation of Norleucine for Methionine
-18	Succinimide formation from aspartic acid
-17	Pyroglutamic Acid formed from Gln
-17	N-pyrrolidone carboxyl (N terminus)
-17	N alpha -(gamma-Glutamyl)-lysine
-17	N-(beta-Aspartyl)-Lysine (Crosslink)
-17	Succinimide formation from asparagine
-17	S-carbamoylmethylcysteine cyclization (N-terminus)
-16	Pyruvoyl- (Serine)
-5	Crosslink between Arg and His sidechains
-4	3,3',5,5'-TerTyr (Crosslink)
-2	Formylglycine (from serine)
-2	Disulphide bond formation (Cystine)
-2	S-(2-Histidyl)- (Crosslinked to Cysteine)
-2	S-(3-Tyr) (Crosslinked to Cysteine)
-2	3,3'-BiTyr (Crosslink)
-2	IsodiTyr (Crosslink)
-1	Allysine (from Lysine)
-1	Amide formation (C terminus)
-1	Oxidation of lysine (to aminoadipic semialdehyde)
1	Deamidation of Asparagine and Glutamine to Aspartate and Glutamate
1	Citruline (from Arginine)
2	Cysteine x2, reduction of Cystine (Cys-Cys)
2	Reduction of indole double bond of Trp
4	Oxidation of Trp to kynurenine
12	Lysine epsilon amino to imine
12	Cysteine (N-term) formaldehyde adduct (Cys to Thioproline conversion)
12	Formaldehyde adduct of Trp
13	Syndesine (from Lysine)
13	CM-Cys vs PAM-Cys
14	Methylation (N terminus, N epsilon of Lysine, O of Serine, Threonine or C terminus, N of Asparagine)
14	CAM-Cys vs PAM-Cys
14	Methylation (methyl esterification of Asp and Glu side chains)
15	delta-Hydroxy-allysine (from Lysine)
15	Oxidation of lysine (to aminoadipic acid)
16	Hydroxylation (of delta C of Lysine, beta C of Tryptophan, C3 or C4 of Proline, beta C of Aspartate)
16	Oxidation of Methionine (to Sulphoxide)
16	3,4-Dihydroxy-Phenylalanine (from Tyrosine) (DOPA)
16	Oxohistidine (from histidine)
16	Sulfenic Acid (from Cysteine)
16	Oxidation of proline (to gamma-glutamyl semialdehyde)
22	Sodium
28	Ethyl
28	N,N dimethylation (of Arginine or Lysine)
28	2,4-BisTrp-6,7-dione (from Tryptophan)
28	Formylation (CHO)
30	6,7 Dione (from Tryptophan)
32	3,4,6-Trihydroxy-Phenylalanine (from Tyrosine) (TOPA)
32	3,4-Dihydroxylation (of Proline)
32	Oxidation of Methionine (to Sulphone)
32	Oxidation of proline (to glutamic acid)
32	Double oxidation of Trp
34	3-Chlorination (of Tyrosine with 35Cl)
36	3-Chlorination (of Tyrosine with 37Cl)
38	Potassium
42	Acetylation (N terminus, N epsilon of Lysine, O of Serine) (Ac)
42	N-Trimethylation (of Lysine)
43	Carbamylation
44	disodium
45	Nitro (NO2)
46	beta-Methylthio-aspartic acid
48	Cysteic acid, oxidation of cysteine
51	Piperidine adduct to C-terminal Cys
56	t-butyl ester(OtBu) and t-butyl (tBu)
57	Glycyl (-G-,-Gly-)
57	Carboxamidomethyl (on Cysteine)
58	Carboxymethyl (on Cysteine)
60	sodium + potassium
64	Selenocysteine (from Serine)
67	Asp transamidation with piperidine
68	3,5-Dichlorination (of Tyrosine with 35Cl)
69	Dehydroalanine (Dha)
70	3,5-Dichlorination (of Tyrosine with mixture of 35Cl and 37Cl))
70	Pyruvate
71	Sarcosyl
71	Alanyl (-A-, -Ala-)
71	Acetamidomethyl (Acm)
71	Propionamide or Acrylamide adduct
72	3,5-Dichlorination (of Tyrosine with 37Cl)
74	S-(sn-1-Glyceryl) (on Cysteine)
74	Glycerol Ester (on Glutamic acid side chain)
75	Glycine (G, Gly)
76	Phenyl ester (OPh) (on acidic)
76	Beta mercaptoethanol adduct
78	3-Bromination (of Tyrosine with 79Br)
78	L-o-bromination of Phe with 79Br
80	L-o-bromination of Phe with 81Br
80	Sulphonation (SO3H) (of PMC group)
80	Sulphation (of O of Tyrosine)
80	Phosphorylation (O of Serine, Threonine, Tyrosine and Aspartate, N epsilon of Lysine)
80	3-Bromination (of Tyrosine with 81Br)
82	Cyclohexyl ester (OcHex)
83	Dehydroamino butyric acid (Dhb)
83	Homoseryl lactone
85	2-Aminobutyric acid (Abu)
85	2-Aminoisobutyric acid (Aib)
85	Gamma Aminobutyryl
86	t-butyloxymethyl (Bum)
86	Diaminopropionyl
87	N-(4-NH2-2-OH-butyl)- (of Lysine) (Hypusine)
87	Seryl (-S-, -Ser-)
88	t-butylsulfenyl (StBu)
89	Alanine (A, Ala)
89	Sarcosine (Sar)
90	Anisyl
90	Benzyl (Bzl) and benzly ester (OBzl)
93	1,2-ethanedithiol (EDT)
95	Dehydroprolyl
96	Trifluoroacetyl (TFA)
97	N-hydroxysuccinimide (ONSu, OSu)
97	Prolyl (-P-, -Pro-)
98	Cysteic acid x2, oxidation of cystine
98	Tetramethylguanidinium termination by-product on amine
98	Phosphate/sulphate adduct of proteins
99	Valyl (-V-, -Val-)
99	Isovalyl (-I-,-Iva-)
100	t-Butyloxycarbonyl (tBoc)
101	Threoyl (-T-, -Thr-)
101	Homoseryl (-Hse-)
103	Cystyl (-C-, -Cys-)
104	4-Methylbenzyl (Meb)
104	Benzoyl (Bz)
105	Serine (S, Ser)
105	Pyridylethylation of cysteine
106	HMP (hydroxymethylphenyl) linker
106	Thioanisyl
106	Thiocresyl
111	2-Piperidinecarboxylic acid (Pip)
111	Pyroglutamyl
113	Hydroxyprolyl (-Hyp-)
113	Isoleucyl (-I-, -Ile-)
113	Leucyl (-L-, -Leu-)
113	Norleucyl (-Nle-)
114	Asparagyl (-N-, -Asn-)
114	t-amyloxycarbonyl (Aoc)
114	Ornithyl (-Orn-)
115	Proline (P, Pro)
115	Aspartyl (-D-, -Asp-)
117	Succinyl
117	Valine (V, Val)
117	Hydroxybenzotriazole ester (HOBt)
118	Dimethylbenzyl (diMeBzl)
119	Threonine (T, Thr)
119	Cysteinylation
120	Benzyloxymethyl (Bom)
120	p-methoxybenzyl (Mob, Mbzl)
121	4-Nitrophenyl, p-Nitrophenyl (ONp)
121	Cysteine (C, Cys)
125	Chlorobenzyl (ClBzl)
126	Iodination (of Histidine[C4] or Tyrosine[C3])
126	octanoylation
128	Glutamyl (-Q-, -Gln-)
128	Lysyl (-K-, -Lys-)
129	Glutamyl (-E-, -Glu-)
129	O-Methyl Aspartamyl
130	N alpha -(gamma-Glutamyl)-Glu
131	Norleucine (Nle)
131	Hydroxyproline (Hyp)
131	Isoleucine (I, Ile)
131	Leucine (L, Leu)
131	Methionyl (-M-, -Met-)
131	Hydroxy Aspartamyl
131	bb-dimethyl Cystenyl
132	Asparagine (N, Asn)
132	Pentoses (Ara, Rib, Xyl)
133	Aspartic Acid (D, Asp)
134	Benzyloxycarbonyl (Z)
134	Adamantyl (Ada)
135	p-Nitrobenzyl ester (ONb)
137	Histidyl (-H-, -His-)
142	N-methyl Glutamyl
142	N-methyl Lysyl
143	O-methyl Glutamyl
143	Diphthamide (from Histidine)
144	Hydroxy Lysyl (-Hyl-)
145	Methyl Methionyl
146	Glutamine (Q, Gln)
146	Deoxyhexoses (Fuc, Rha)
146	Lysine (K, Lys)
146	Pentosyl
146	Aminoethyl Cysteinyl (AECys)
147	4-Glycosyloxy- (pentosyl,C5) (of Proline)
147	Glutamic Acid (E, Glu)
147	Phenylalanyl- (-F-, -Phe-)
147	Methionyl Sulfoxide
148	Pyridyl Alanyl
149	2-Nitrobenzoyl (NBz)
149	Methionine (M, Met)
149	Fluorophenylalanyl
150	Dimethoxybenzyl Trp
153	2-Nitrophenylsulphenyl (Nps)
154	4-Toluenesulphonyl (Tosyl, Tos)
154	3-nitro-2-pyridinesulfenyl (Npys)
155	Histidine (H, His)
156	3,5-Dibromination (of Tyrosine with 79Br)
156	Arginyl (-R-, -Arg-)
157	Citrulline
158	3,5-Dibromination (of Tyrosine with mixture of 79Br and 81Br)
159	Dichlorobenzyl (Dcb)
160	3,5-Dibromination (of Tyrosine with 81Br)
160	Carboxyamidomethyl Cystenyl
161	Hexosamines (GalN, GlcN)
161	Carboxymethyl cysteine (Cmc)
161	Carboxymethyl Cystenyl
161	Methylphenylalanyl
162	Inositol
162	N-Glucosyl (N terminus or N epsilon of Lysine) (Aminoketose)
162	O-Glycosyl- (to Serine or Threonine)
162	Linker attached to peptide in Fmoc peptide synthesis
162	Hexoses (Fru, Gal, Glc, Man)
163	Tyrosinyl (-Y-, -Tyr-)
163	MethionylSulphone
165	Phenylalanine (F, Phe)
166	2,4 -dinitrophenyl (Dnp)
166	Pentaflourophenyl (Pfp)
166	Diphenylmethyl (Dpm)
167	Phospho Seryl
169	2-Chlorobenzyloxycarbonyl (ClZ)
169	Napthyl acetyl
170	N-acetyl Lysyl
170	N-methyl Arginyl
172	Ethanedithiol/TFA cyclic adduct
173	Carboxy Glutamyl (Gla)
174	Arginine (R, Arg)
174	Acetamidomethyl Cystenyl
174	Acrylamidyl Cystenyl
176	N-Glucuronyl (N terminus)
177	delta-Glycosyloxy- (of Lysine) or beta-Glycosyloxy- (of Phenylalanine or Tyrosine)
177	4-Glycosyloxy- (hexosyl,C6) (of Proline)
177	Benzyl Seryl
177	N-methyl Tyrosinyl
178	a-N-Gluconoylation (His Tagged proteins)
179	p-Nitrobenzyloxycarbonyl (4Nz)
179	2,4,5-Trichlorophenyl
180	2,4,6-trimethyloxybenzyl (Tmob)
180	Xanthyl (Xan)
181	Tyrosine (Y, Tyr)
182	Chlorophenylalanyl
182	Mesitylene-2-sulfonyl (Mts)
183	AEBSF
184	Isopropyl Lysyl
186	Tryptophanyl (-W-, - Trp-)
186	Carboxymethyl Lysyl
188	N-Lipoyl- (on Lysine)
190	Matrix alpha cyano MH+
191	Benzyl Threonyl
193	Benzyl Cystenyl
197	Napthyl Alanyl
198	Succinyl Aspartamyl
201	HMP (hydroxymethylphenyl)/TFA adduct
203	N-acetylhexosamines (GalNAc, GlcNAc)
204	Tryptophan (W, Trp)
204	Cystine ((Cys)2)
204	Farnesylation
206	S-Farnesyl-
206	Myristoylation-4H (2 double bonds)
208	Myristoleylation (myristoyl with one double bond)
208	Pyridylethyl Cystenyl
210	Myristoylation
212	4-Methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr)
213	2-Bromobenzyloxycarbonyl (BrZ)
214	Formyl Tryptophanyl
219	Benzyl Glutamyl
219	Anisole Adducted Glutamyl
222	9-Fluorenylmethyloxycarbonyl (Fmoc)
222	S-cystenyl Cystenyl
226	Biotinylation (amide bond to lysine)
226	Dimethoxybenzhydryl (Mbh)
229	N-Pyridoxyl (on Lysine)
231	Pyridoxal phosphate (Schiff Base formed to lysine)
233	Dansyl (Dns)
233	Nicotinyl Lysyl
238	2-(p-biphenyl)isopropyl-oxycarbonyl (Bpoc)
238	Palmitoylation
242	Triphenylmethyl (Trityl, Trt)
243	Tyrosinyl Sulphate
243	Phospho Tyrosinyl
252	Pbf (pentamethyldihydrobenzofuransulfonyl)
252	3,5-Diiodination (of Tyrosine)
258	a-N-6-Phosphogluconoylation (His Tagged proteins)
259	N alpha -(gamma-Glutamyl)-Glu2
266	O-GlcNAc-1-phosphorylation (of Serine)
266	Stearoylation
266	Pmc (2,2,5,7,8- Pentamethylchroman-6-sulphonyl)
272	Geranylgeranylation
272	Monomethoxytrityl
276	S-Geranylgeranyl
289	5'phos dCytidinyl
289	iodo Tyrosinyl
290	Aldohexosyl Lysyl
291	Sialyl
291	N-acetylneuraminic acid (Sialic acid, NeuAc, NANA, SA)
304	5'phos dThymidinyl
305	5'phos Cytidinyl
305	Glutathionation
306	O-Uridinylylation (of Tyrosine)
306	5'phos Uridinyl
307	N-glycolneuraminic acid (NeuGc)
307	S-farnesyl Cystenyl
313	5'phos dAdenosyl
324	O-pantetheinephosphorylation (of Serine)
327	SucPhencarb Lysyl
329	5'phos dGuanosyl
329	5'phos Adenosinyl
329	O-5'-Adenosylation ( of Tyrosine)
339	4'-Phosphopantetheine
342	S-palmityl Cystenyl
345	5'phos Guanosyl
354	Biotinyl Lysyl
359	Fluorescein labelling of peptide N-terminal using NHS ester
365	Hex-HexNAc
388	N alpha -(gamma-Glutamyl)-Glu3
391	Dioctyl Phthalate
395	PMC Lysyl
409	Aedans Cystenyl
413	Dioctyl Phthalate Sodium Adduct
415	di-iodo Tyrosinyl
423	PMC Arginyl
454	S-Coenzyme A
457	AMP Lysyl
470	3,5,3'-Triiodothyronine (from Tyrosine)
524	S-(sn-1-Dipalmitoyl-glyceryl)- (on Cysteine)
541	S-(ADP-ribosyl)- (on Cysteine)
541	N-(ADP-ribosyl)- (on Arginine)
541	O-ADP-ribosylation (on Glutamate or C terminus)
541	ADP-rybosylation (from NAD)
587	S-Phycocyanobilin (on Cysteine)
617	S-Heme (on Cysteine)
648	N theta -(ADP-ribosyl) diphthamide (of Histidine)
657	NeuAc-Hex-HexNAc
783	O-8 alpha-Flavin [FAD])- (of Tyrosine)
784	S-(6-Flavin [FAD])- (on Cysteine)
784	N theta and N pi-(8alpha-Flavin) (on Histidine)
893	(Hex)3-HexNAc-HexNAc
1,039	(Hex)3-HexNAc-(dHex)HexNAc