ABRF : Research Groups

MicroArray Research Group (MARG)

The goal of the Microarray Research Group is to provide both academic and industrial scientists useful information and guidance in the use of various microarray platforms and applications in their research. The main focus of the MARG is to promote communication and cooperation among core laboratories providing microarray and data analysis services. In addition, the MARG is charged with conducting studies to help assess technological advancements and provide information about these technologies to all interested parties. Information developed and communicated by the MARG should be used to help laboratories evaluate their performance and achieve the highest quality results possible from the use of microarray technologies. In order to accomplish these goals the MARG will also strive to provide ways for sharing information relevant to the administration of facility laboratories that provide microarray technologies as a shared resource.

Current Membership

Herbert Auer - IRB Barcelona
Dr. Don A. Baldwin (Co-chair) - University of Pennsylvania
Dr Natalia G.Reyero Vinas - Jackson State University
Dr Christina A Harrington (Co-Chair) - Oregon Health & Science Univesity
Nadereh Jafari - Northwestern Universtiy
Nalini Raghavachari - NIH
Dr. Wei Wang - Cornell University
Jack Simpson (EB liaison) - SAIC - Frederick

Studies

1)	MARG 2008 Study - View Announcement (8K)
2)	2007 MARG Research Project Powerpoint Presentation - View Document (2,623K)
3)	2004 RESEARCH PROJECT PROTOCOLS - Ambion- MessageAmp II aRNA kit (48K) - Enzo BioArray RNA Amplification labeling system (126K) - Nugen Ovation Biotin system (27K) - AffymetrixTwo-cycles labeling Assay (140K) - Standard protocol

Activities

1)	2010 MARG session - microRNA Profiling: Platform Comparison; microRNA Synthetic Reference Project - View Presentation (pdf)
2)	2010 MARG session: MARG Activities and New Wiki Discussion Forum - View Document (909K)
3)	MARG wiki link - technology discussion forum - View Document
4)	2008 MARG Talk - 2008 MARG Talk
5)	2007 MARG Educational Session - View Document (6,826K)
6)	At the national ABRF meeting the MARG convened a roundtable to discuss data comparability among commercial microarray platforms. A distinguished acadmic panel asked questions of bioinformaticists representing the microarray industry leaders. The discussion centered around 10 questions created by the academic panel and also addressed questions and comments from the meeting participants. Below are the transcripts from this meeting. - View Document (117K) - View Document (63K)

Electronic Posters

1)	2009 MARG Study Poster - microRNA Profiling - View Document (620K)
2)	2008 MARG Survey Poster - 2008 MARG Survey Poster - Survey Summary
3)	2007 MARG Research Project Poster - View Document (2,193K)
4)	Evaluation of Small Sample Nucleic Acid Amplification Technologies for Gene Expression Profiling. For more information and requests for the slide presentation please email Herber Auer at auerh@ccri.net - View Document (50K)
5)	Taking the Pulse of the Microarray Field: The Microarray Survey 2005. For more information and requests for the slide presentation please email kevin-knudtson@uiowa.edu - View Document (204K)
6)	Comparing GeneChip Data Generated in Different Laboratories (Reid et al.) - View Document (224K)
7)	A Current Profile of Microarray Laboratories: The Microarray Survey 2003 - View Document (418K)
8)	Microarray Variability Study 2002 - View Document (1,486K)
9)	Estimation and Reduction of the Bias Caused by RNA Degradation in Microarray Analysis - View Document (71K)
10)	A Current Profile of Microarray Laboratories: The Microarray Survey 2001 - View Document (106K)
11)	The State of the Art of Microarray Analysis: The Microarray Survey 1999 - View Document (184K)

Publications

1)	Grills, G. (1999). Problems and Pleasures of Implementing Microarray Technologies. J. Biomolecular Techniques 10(2), 105 (abstract).
2)	Albertson, H.(1999).Microarrays in a Shared Facility - Practical and Scientific Experiences from the Huntsman Cancer Institute. J. Biomolecular Techniques 10(2), 105 (abstract).
3)	Massimi, A. (1999).Implementation of a Custom cDNA Microarray Facility at AECOM. J. Biomolecular Techniques 10(2), 105 (abstract).
4)	Sandmeyer, S. (1999).A Userís-Eye View of the Affymetrix Gene Expression System: The Early Days. J. Biomolecular Techniques 10(2), 105 (abstract).
5)	Grills, G., Griffin, C., Heck, D., Lilley, K., Massimi, A., Sandmeyer, S., Bao, Y., and J.I. Van Ee (2000).The State of the Art of Microarray Analysis: A Profile of MicroarrayLaboratories.J. Biomolecular Techniques11(1), 30 (abstract).
6)	Bumgarner, R. (2000). DNA Arrays: Technologies, Applications, and Data Analysis. J. Biomolecular Techniques 11(1), 35 (abstract).
7)	Grills, G., Bumgarner, R., Delrow, J., Lilley, K. Massimi, A., Bao, Y., Knudtson, K., VanEe, J. andC. Griffin (2000).The State of the Art of Microarray Research: Results of the ABRF Microarray Research Group Studies.Microb. Comp. Genomics(abstract, in press).
8)	Grills, GS. Problems and pleasures of implementing microarray technologies. J. Biomol. Tech. 1999; 10(2):105.
9)	Albertson, H. Microarrays in a Shared Facility - Practical and Scientific Experiences from the Huntsman Cancer Institute. J. Biomol. Tech. 1999; 10(2), 105 (abstract).
10)	Massimi, A. Implementation of a Custom cDNA Microarray Facility at AECOM. J. Biomol. Tech. 1999; 10(2), 105.
11)	Sandmeyer, S. A Userís-Eye View of the Affymetrix Gene Expression System: The Early Days. J. Biomol. Tech. 1999; 10(2), 105.
12)	Grills GS, Griffin C, Heck D, Lilley K, Massimi A, Sandmeyer S, Bao Y, VanEe JI. The state of the art of microarray analysis: a profile of microarray laboratories. J. Biomol. Tech. 2000; 11(1):30. - Web poster, last updated 8/23/00
13)	Bumgarner, R. (2000). DNA Arrays: Technologies, Applications, and Data Analysis. J. Biomol. Tech. 2000; 11(1), 35 (abstract).
14)	Grills GS, Griffin C, Lilley K, Massimi A, Bao Y, VanEe JI. A profile of microarray laboratories. Proceedings of the Northwest Microarray Conference 2000.
15)	Grills GS, Burngarner R, Delrow J, Lilley K, Massimi A, Bao Y, Knudtson K, VanEe JI, Griffin C. The state of the art of microarray research: results of the ABRF Microarray Research Group studies. 12th International Genome Sequencing and Analysis Conference 2000; 10.
16)	Grills GS, Griffin C, Massimi A, Lilley K, Knudtson K, VanEe JI. A current profile of microarray laboratories: results of the 2000-2001 ABRF Microarray Research Group survey of laboratories using microarray technologies. J. Biomol. Tech. 2000; 11(4):225. - Web poster, last updated 6/1/01
17)	Knudtson KL, Griffin C, Brooks A, Iacobas A, Johnson K, Khitrov G, Lilley K, Massimi A, Viale A, Zhang W, Bao Y, Grills GS, Thaler H, Cox C. Factors contributing to variability in DNA microarray results: the ABRF Microarray Research Group 2002 study. J. Biomol. Tech. 2002; 108. - Poster Updated 5/02 (1,486K)

Membership History

Member Name	Organization	Details
Mr Jason P Affourtit	The Jackson Laboratory	Member: 03/04 - 09/04
Herbert Auer	IRB Barcelona	Chair: 02/05 - 02/06 Member: 03/04 - 02/05
Dr. Yongde Bao	Univ of Virginia Sch of Med	Ad hoc: 01/99 - 01/00 Ad hoc: 03/01 - 04/02
Dr Andrew I Brooks	UMDNJ/Rutgers	Chair: 05/02 - 03/04 Member: 03/01 - 03/02 Ad hoc: 02/05 - 02/06 Co-Chair: 03/04 - 02/05
Dr Nancy D Denslow	Univ of Florida-Gainesville	EB Liaison: 02/05 - 03/09
Jaime Gill		Member: 06/03 - 03/04
Chandi A. Griffin	Bionovo, Inc	Member: 01/99 - 02/01 Member: 04/02 - 02/05 Ad hoc: 02/05 - 02/07 Co-Chair: 03/01 - 03/02
George S. Grills	Cornell University	Chair: 07/99 - 03/00 Member: 01/99 - 07/99 Ad hoc: 03/01 - 03/07 Co-Chair: 03/00 - 03/01
Dr. Susan Hester	US Environmental Protection Agency	emeritus: 04/04 - 03/09
Dr Dumitru A. Iacobas	Albert Einstein Coll of Med	Member: 03/01 - 06/03 Ad hoc: 06/03 - 03/04 Ad hoc: 08/04 - 08/04
Kevin A. Johnson	The Jackson Laboratory	Member: 03/01 - 06/03 Ad hoc: 06/03 - 06/04
Mrs. Cassie Keener	moved - no address	Member: 06/03 - 03/04
Dr Greg Khitrov	Mount Sinai Medical Center	Member: 06/04 - 05/06
Dr. Kevin L. Knudtson	Univ of Iowa	ChairCo-Chair: 03/01 - 04/02 Member: 05/02 - 02/05 Ad hoc: 02/05 - 02/07 Ad hoc: 01/00 - 03/01
Dr Shawn E Levy	Vanderbilt University	Member: 11/02 - 03/04
Dr Kathryn S Lilley	University of Cambridge	Member: 01/99 - 01/00 Ad hoc: 01/00 - 04/02 EB Liason: 03/04 - 02/05
Mr. Aldo B Massimi	Albert Einstein College of Medicine	Member: 08/99 - 02/02 Ad hoc: 02/02 - 09/08
Paul T Morrison	MBCF @ Dana-Farber Cancer Institute	EB Liason: 01/99 - 01/00
Dr. Norma J. Nowak	SUNY Buffalo and RPCI	Member: 07/02 - 03/04
Dr. Steven Potter	Children's Hospital Medical Center	Member: 07/07 - 03/09
Dr Marco F Ramoni	Harvard Medical School	Member: 08/04 - 02/05
Dr. Laura H Reid	Expression Analysis, Inc.	Memberretired: 05/05 - 03/08
Caprice Rosato	Oregon State Univ	Member: 10/06 - 05/07
Laurey Steinke	University of Nebraska Medical Center	EB Liason: 01/00 - 03/01
Theodore W Thannhauser	United States Department of Agriculture/Agricultural Research Service	EB Liason: 03/01 - 03/04
Dr. Jay P. Tiesman	Procter & Gamble	Member: 06/04 - 01/09
James Van Ee	Cornell University	Ad hoc: 01/99 - 04/01
Agnes Viale	Memorial Sloan Kettering Cancer Ctr.	Member: 03/01 - 03/04 Member: 04/04 - 12/07

Links

MARG wiki - technology discussion forum
- MARG wiki

Microarray Information Resource
- View Link