ABRF Research Groups
Research Groups or RGs for short are organized by ABRF members to advance specific biotechnologies and analytical techniques for the benefit of core and research laboratories. This is done primarily by developing research studies whereby participating laboratories can gauge their ability to perform a given analytical technique(s) and, importantly, to gauge the effectiveness of that technique or methodology in real laboratory situations. Currently there are fourteen RGs whose areas of expertise covers a wide range of biotechnologies including: antibody technologies, glycoproteins, proteomics, protein sequencing, molecular interactions, metabolomics, nucleic acids and DNA sequencing, genomics, microarray technologies and light microscopy.
The menu to the left lists all the active research groups. If you are interested in their research studies or want to become involved in a research group check out their web pages and contact one of their members for more information.
Research Group Studies
| Research Groups | Studies in Preparation | Active Studies | |
|---|---|---|---|
| ARG | Antibody Technologies | Calling All Antibody Developers | |
| DSRG | DNA Sequencing |
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| GVRG | Genomic Variation | WGA fromm FFPE Samples | ABRF NGS Study: Objectively assess the technical performance of different next-generation sequencing technologies for RNA analyses. |
| gPRG | Glycoprotein | ||
| LMRG | Light Microscopy | PSF and Spectral Imaging Study | |
| MRG | Metabolomics | ||
| MARG | MicroArray | ABRF NGS Study: Objectively assess the technical performance of different next-generation sequencing technologies for RNA analyses. | |
| MIRG | Molecular Interactions | ||
| NARG | Nucleic Acids | DNA methylation and miRNA profiles across degraded samples | |
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Next Gen Sequencing Multi-RG Study |
Assess the performance of different next-generation sequencing technologies for nucleic acid analyses. To evaluate the various data analysis methods. To create a publicly available tool for assessment of data from these instruments as compared to an established set of sequencing data from a standardized protocol. |
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| PERG | Protein Expression | ||
| PSRG | Protein Sequencing | Sample preparation and terminal sequencing of a protein mixture | |
| iPRG | Proteome Informatics | Detecting modified peptides in a complex mixture | |
| PRG | Proteomics | Longitudinal Viariability Study | |
| sPRG | Proteomics Standards | Comprehensive PTM peptide standard | |
Research Group Publications
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Quality Assurance Testing for Modern Optical Imaging Systems
Robert F. Stack, Carol J. Bayles, Anne-Marie Girard, Karen Martin, Cynthia Opansky, Katherine Schulz and Richard W. Cole
Microscopy and Microanalysis (2011) DOI:10.1017/S1431927611000237 -
The ABRF Proteomics Research Group Studies: Educational exercises for qualitative and quantitative proteomic analyses
Friedman DB, Andacht TM, Bunger MK, Chien AS, Hawke DH, Krijgsveld J, Lane WS, Lilley KS, Maccoss MJ, Moritz RL, Settlage RE, Sherman NE, Weintraub ST, Witkowska HE, Yates NA, Turck CW
Proteomics (2011) vol. 11 (8) pp. 1371-81 -
ABRF-PRG07: Advanced Quantitative Proteomics Study
Falick AM, Lane WS, Lilley KS, Maccoss MJ, Phinney BS, Sherman NE, Weintraub ST, Witkowska HE, Yates NA
JBT (2011) vol. 22 (1) pp. 21-6
Featured Research Group
This year marks the tenth birthday of the Proteomics Research Group (PRG). The PRG broke from tradition this year and hosted a survey rather than the traditional laboratory-based research study which uncovered a few surprises. This group has been very productive, presenting their research study results at ASMS and HUPO and they are publishing their latest study in the journal Molecular and Cellular Proteomics.
